June 3, 2026
5 Nebraska passengers cleared home · US inconclusive case negative · Arizona death unrelated
CDC confirms 5 of 18 Nebraska Quarantine Unit passengers have met criteria to complete monitoring at home. 13 remain at NQU. The US passenger who had inconclusive test results (one positive, one negative from two labs) has been confirmed not infected. Separately, Mohave County, Arizona confirms a death from Sin Nombre hantavirus in Kingman — health officials explicitly state this case is not related to the MV Hondius Andes virus outbreak. Sin Nombre does not spread person to person. The 42-day monitoring window for those last exposed May 10 closes June 21.
May 25, 2026
Second Spain case confirmed · Netherlands crew member positive · ECDC reports 12 total
Spain confirms a second hantavirus case — a close contact of an MV Hondius passenger who has been in preventive quarantine at Gómez Ulla Military Hospital in Madrid since May 10. Separately, WHO confirms a crew member who disembarked in Tenerife and was repatriated to the Netherlands tested positive. ECDC updates total to 12 cases: 10 confirmed, 2 probable. No new deaths since May 2.
May 22, 2026
Spain confirmed as 10th case · Canada upgraded · ECDC reports 11 total
CDC confirms three new cases since disembarkation: France (symptomatic during repatriation), Spain (positive on arrival, currently asymptomatic), and Canada (positive, mild symptoms). ECDC updates total to 11 cases — 9 confirmed, 2 probable. One inconclusive US case is being retested after conflicting results from two laboratories. No new deaths reported.
May 21, 2026
CDC issues formal quarantine orders for 2 Nebraska passengers
CDC issues federal quarantine orders — signed by Acting Director Jay Bhattacharya — for 2 of the 18 MV Hondius passengers at the Nebraska Biocontainment Unit. All 18 passengers have requested to remain at the facility through May 31, the 21-day monitoring mark. The 2 Atlanta passengers transferred to Nebraska after being medically cleared, making Nebraska the sole US quarantine site. No confirmed US cases.
May 18, 2026
MV Hondius docks in Rotterdam for disinfection
The ship arrives at the Port of Rotterdam at ~10:00 a.m., escorted by a tug and Dutch police boat, ending its troubled 47-day voyage. 25 crew and 2 medical staff on board enter immediate quarantine. No symptomatic individuals present. The vessel will undergo full decontamination. WHO reports 440 people across 30+ countries are now being monitored.
May 16, 2026
Canada confirms case: Vancouver Island passenger
Public Health Agency of Canada confirms a passenger from Vancouver Island, British Columbia, tested positive for Andes hantavirus — the 9th confirmed case globally. The individual had been under quarantine and is experiencing mild symptoms. ECDC updates total to 12 cases (9 confirmed, 2 probable, 1 inconclusive).
May 14–15, 2026
Situation stabilising: no new cases since May 8
ECDC reports 11 total cases (8 confirmed, 2 probable, 1 inconclusive). No new cases or deaths since the previous update. Ship en route to Netherlands for decontamination. WHO and CDC maintain low pandemic risk assessment.
May 10–11, 2026
Ship docks in Tenerife: full disembarkation
After Spain grants approval, MV Hondius arrives in Canary Islands. All passengers disembark. 16 Americans fly to Omaha, Nebraska; 2 to Atlanta. France confirms first case at Bichat hospital (Paris). 42-day quarantine decreed.
May 10, 2026
British paratroopers parachute into Tristan da Cunha
6 paratroopers, an RAF consultant, and an army nurse parachute onto the island, the only option given no airstrip and the nearest port over a week away by sea, to care for the probable British case with oxygen and supplies.
May 6–7, 2026
Medical evacuations from Cape Verde
Two air ambulance flights carry symptomatic patients to the Netherlands. Three more evacuated including the ship's doctor. Switzerland confirms a case; sequence published as ANDV/Switzerland/Hu-3337/2026.
May 4–5, 2026
Andes virus confirmed by gene sequencing
WHO reports 7 cases: 2 lab-confirmed, 5 suspected. Gene sequencing identifies the Andes strain. WHO ships 2,500 diagnostic kits to 5 countries and deploys an expert on board the ship.
May 2, 2026
WHO notified: outbreak declared
United Kingdom notifies WHO under International Health Regulations (IHR). WHO begins multi-country coordination. CDC classifies response as Level 3 emergency.
May 2, 2026
Third death: German woman dies on board
A German passenger dies aboard the MV Hondius four days after falling ill, showing signs of pneumonia. Her body remains on the ship as it continues toward Cape Verde. This is the last death reported in the outbreak.
April 26, 2026
Second death: Dutch widow dies in Johannesburg
Her retrospective sample tests positive for Andes virus, triggering the initial WHO outbreak signal. This is the key event that alerts international health authorities.
April 22–24, 2026
Saint Helena disembarkation: 30 passengers leave
The Dutch widow of the index case disembarks and boards a flight to Cape Town, transiting Johannesburg. 82 passengers on the Airlink flight are later identified as contacts. A KLM flight is also traced.
April 14, 2026
Disembarkation at Tristan da Cunha
A British passenger leaves the ship at one of the most remote inhabited places on Earth. Develops symptoms April 28 and is later classified as a probable case. British paratroopers later parachute in with medical supplies.
April 11, 2026
First death: index case
70-year-old Dutch passenger dies aboard. Hantavirus not yet suspected, no samples collected. Human-to-human transmission is already underway at this point.
Early April 2026
MV Hondius sets sail
Ship departs with 147 passengers and crew from 23 nationalities. Berths priced €14,000–€22,000. Illness onset in the cluster spans April 6–28, consistent with a 2-week incubation period from initial infection.
Nov 27, 2025 – Apr 1, 2026
Index case exposure window
Dutch passenger completes a 4-month road trip through Chile, Uruguay, and Argentina. Returns to Argentina only 4 days before the ship departs. Believed to have contracted Andes virus from contact with infected rodents in the endemic range.